Schools in Ahmedabad are run either by the municipal corporation, or privately by entities, trusts and corporations. Most schools are affiliated with the Gujarat Secondary and Higher Secondary Education Board. Some schools, like the Delhi Public School and the Kendriya Vidyalayas, are associated with the Central Board for Secondary Education. A large number of colleges in the city are affiliated with Gujarat University. Other deemed universities in Ahmedabad include the Nirma University of Science & Technology and the Dr. Babasaheb Ambedkar Open University. The prestigious Gujarat Vidyapith was established in 1920 by Mahatma Gandhi; it was among the first institutions of higher learning managed entirely by Indians, despite British control.

Prestigious institutions such as the Indian Institute of Management, the National Institute of Design, the Mudra Institute of Communications, the National Institute of Fashion Technology, the Entrepreneurship Development Institute of India and the Center for Environmental Planning and Technology are located in Ahmedabad. Many national academic and scientific institutions, such as the Physical Research Laboratory and the Space Applications Centre of the Indian Space Research Organisation, were established in the 1960s largely through the efforts of prominent astrophysicist and industrialist Vikram Sarabhai. The Ahmedabad Management Association is a notable institution established to impart management training and experience to young students and professionals. A plan to open a satellite campus of the Indian Institute of Technology, Bombay, with a capacity of around 4,000 students, is on the papers. The IIT will offer courses with a focus on the skilled-labour needs of Gujarat, such as textiles, and aeronautical, marine, and ship engineering. B.J.Medical College started in 1871, is one of the prime medical schools of the country which has given famous doctors who work all over the world