Ahmedabad is home to prestigious institutes like the Indian Institute of Management, National Institute of Design, Mudra Institute of Communications Ahmedabad, National Institute of Fashion Technology and the Center for Environmental Planning and Technology, and B. J. Medical College.

A large number of colleges in the city are affiliated to the Gujarat University and offer courses in Medicine, Engineering, Arts, Science, Commerce, Law and Management. Other deemed universities in Ahmedabad are Gujarat Vidyapeeth, Nirma University of Science & Technology and Dr. Babasaheb Ambedkar Open University.

Many academic and scientific institutions of national repute were set up in Ahmedabad due to the efforts of Vikram Sarabhai. The most important of these are the Physical Research Laboratory and the Space Applications Centre which fall under the Ahmedabad centre of the Indian Space Research Organization. The Vikram Sarabhai Community Science Centre aims to educate children about the various aspects of science.